ncRNA name | Il-1β siRNA |
ncRNA Category | siRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | siRNA injection, TUNEL assay and immunohistochemistry, qPCR, in situ hybridisation |
Expression pattern | associated |
Functional description | Intravitreal IL-1β inhibitors suppressed chemokine expression following damage and reduced macrophage accumulation and photoreceptor death. |
PubMed ID | 28438165 |
Year | 2017 |
Title | Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration. |
Drug-related ncRNA | NO |
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